This guide contains information about places where you can stop for the night when driving from Louisville, Kentucky to Myrtle Beach, South Carolina. Total distance for the trip is around 655 miles with a driving time of approximately 9 hours 53 mins. Cities and towns with hotels that are on the fastest route between Louisville and Myrtle Beach are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)

55.2 miles from Louisville (54 mins)
606 miles from Myrtle Beach (9 hours 12 mins)
78.7 miles from Louisville (1 hour 17 mins)
579 miles from Myrtle Beach (8 hours 53 mins)
150 miles from Louisville (2 hours 14 mins)
506 miles from Myrtle Beach (7 hours 47 mins)
247 miles from Louisville (3 hours 35 mins)
411 miles from Myrtle Beach (6 hours 22 mins)
360 miles from Louisville (5 hours 21 mins)
305 miles from Myrtle Beach (4 hours 43 mins)
419 miles from Louisville (6 hours 15 mins)
241 miles from Myrtle Beach (3 hours 50 mins)
507 miles from Louisville (7 hours 28 mins)
153 miles from Myrtle Beach (2 hours 33 mins)
586 miles from Louisville (8 hours 36 mins)
67.3 miles from Myrtle Beach (1 hour 19 mins)

Popular Hotels In Myrtle Beach

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Please make sure you read your reservation's cancellation policy!
You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.